Your endocannabinoid system (ECS) consists of two major cannabinoid receptors including:
CB1 – found abundantly in the brain and are involved in the modulation of emotion, memory, pain, movement, and the autonomic and endocrine system.
These receptors are the main target for THC cannabinoids.
CB2 – found mainly in immune cells and not highly expressed in your central nervous system, which is why it doesn’t give mind-altering effects. CB2 receptors modulate nerves, neuroinflammation, chronic inflammation, pain, and mood.
These receptors are activated by endocannabinoids produced naturally by your body or by phytocannabinoids found in the cannabis plant world.
Cannabinoid receptors have been discovered in our skin cells, and other parts of the skin, such as the hair follicles, small nerves, and immune cells.
When CBD topical is applied to the skin, it is absorbed through our pores and reaches and interacts with the receptors near where the topical was applied.